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Markus Riessland Selected Research

cyclic hexapeptide(Phe-Phe-Trp-Lys-Thr-Phe)- somatostatin (CHP1)

2/2018Biallelic CHP1 mutation causes human autosomal recessive ataxia by impairing NHE1 function.
1/2018CHP1 reduction ameliorates spinal muscular atrophy pathology by restoring calcineurin activity and endocytosis.

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Markus Riessland Research Topics

Disease

15Spinal Muscular Atrophy (Progressive Muscular Atrophy)
01/2019 - 07/2006
3Neurodegenerative Diseases (Neurodegenerative Disease)
12/2014 - 10/2009
2Motor Neuron Disease (Primary Lateral Sclerosis)
06/2013 - 11/2011
2Neoplasms (Cancer)
06/2013 - 10/2009
1Parkinson Disease (Parkinson's Disease)
10/2019
1Deafness (Deaf Mutism)
02/2018
1Ataxia (Dyssynergia)
02/2018
1Osteoporosis
10/2013
1Osteoporotic Fractures
10/2013
1Infant Death
04/2013
1Neuromuscular Diseases (Neuromuscular Disease)
04/2013
1Respiratory Insufficiency (Respiratory Failure)
04/2010
1Paralysis (Palsy)
04/2010
1Disease Progression
01/2009

Drug/Important Bio-Agent (IBA)

9Proteins (Proteins, Gene)FDA Link
02/2018 - 07/2006
4Histone Deacetylase InhibitorsIBA
06/2013 - 07/2006
2cyclic hexapeptide(Phe-Phe-Trp-Lys-Thr-Phe)- somatostatin (CHP1)IBA
02/2018 - 01/2018
2Actins (F Actin)IBA
10/2013 - 04/2013
2plastinIBA
10/2013 - 04/2013
2Histone Deacetylases (Histone Deacetylase)IBA
01/2009 - 07/2006
2VorinostatFDA Link
08/2006 - 07/2006
1Carrier Proteins (Binding Protein)IBA
10/2019
1A-Form DNA (A-DNA)IBA
10/2019
1CalcineurinIBA
01/2018
1NeurocalcinIBA
01/2017
1CateninsIBA
04/2014
1UbiquitinIBA
04/2014
1quisinostatIBA
06/2013
1Hydroxamic Acids (Hydroxamic Acid)IBA
10/2009
1PanobinostatIBA
10/2009
1RNA (Ribonucleic Acid)IBA
08/2006
1benzamideIBA
08/2006
1Pharmaceutical PreparationsIBA
07/2006

Therapy/Procedure

2Therapeutics
06/2013 - 01/2009
1Drug Therapy (Chemotherapy)
01/2019
1Investigational Therapies (Experimental Therapy)
01/2015